Mechanisms of chylomicron uptake into lacteals
Identifieur interne : 005C69 ( Main/Exploration ); précédent : 005C68; suivant : 005C70Mechanisms of chylomicron uptake into lacteals
Auteurs : J. Brandon Dixon [Géorgie (pays)]Source :
- Annals of the New York Academy of Sciences [ 0077-8923 ] ; 2010-10.
Abstract
Right from birth, the lymphatics play a crucial role in dietary functions. A majority of the lipid absorbed from the newborn's lipid‐rich diet enters the blood circulation through the lymphatic system, which transports triglyceride‐loaded particles known as chylomicrons from the villi of the small intestine to the venous circulation near the heart. In light of the significance of this role, as well as the fact that lipid transport from the gut was one of the earliest discovered functions of the lymphatic vasculature, it is surprising that so little is known about how chylomicrons initially gain access to the lymphatic vessel. This review will focus on the current mechanisms thought to be important in this process and highlight important questions that need to be answered in the future.
Url:
- https://api.istex.fr/document/82B5727BAC5AA6973CFFED5DB801D2C39D030551/fulltext/pdf
- http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3132563
DOI: 10.1111/j.1749-6632.2010.05716.x
Affiliations:
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